Some days it feels like we know very little about how our bodies function

It's amusing to see fitness experts and gurus always taking such strong stances about the right way to lose weight when we're constantly figuring out stuff we didn't know before.

Lowell’s lab has made the surprising discovery that the hunger-inducing neurons that activate these AgRP neurons are located in the paraventricular nucleus — a brain region long thought to cause satiety, or feelings of fullness. This unexpected finding not only provides a critical addition to the overall wiring diagram, but adds an important extension to our understanding of what drives appetite.

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Surprising new clue to the roots of hunger
Researchers are creating a wiring diagram of the complex brain circuits that regulate this intense motivational state While the function of eating is to nourish the body, this is not what actually compels us to seek out food.

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